Which Diagnostic Test For What?
Which Diagnostic Test For What?
There are many different medical tests readily available. For a specific condition or a collection of connected disorders, numerous tests are employed. There are other illnesses for which other tests are frequently employed.
There are many reasons why tests are conducted, including
Screening
How to identify a condition
determining the seriousness of a problem so that a strategy for treatment can be made
Evaluating how well a treatment is working
A test may occasionally have multiple purposes. The presence of anemia, or too few red blood cells, can be detected with a blood test. After treatment, the same test may be conducted once more to see whether the quantity of red blood cells has stabilized. A problem can occasionally be treated concurrently with a screening or diagnostic test.
Most tests fall under one of the six categories listed below.
Examining bodily fluids
The fluids that are typically examined are
Blood
Urine
Cerebrospinal fluid is the fluid that surrounds the brain and spinal cord.
Joint fluid, also known as synovial fluid
Sweat, saliva, and digestive system fluid (such stomach secretions) are examined less frequently. When fluid builds up in the abdomen, generating ascites, or in the space between the two-layered membrane covering the lungs and lining the chest wall (pleura), causing pleural effusion, the fluids that are being tested are occasionally only present if a disease is present.
Test Procedure | Sample Tested | Procedure Description |
---|---|---|
Amniocentesis | Fluid from the sac surrounding the fetus | Analysis of fluid, removed by a needle inserted through the abdominal wall, to detect an abnormality in the fetus |
Arteriography (angiography) | Any artery in the body, commonly in the brain, heart, kidneys, aorta, or legs | X-ray study using radiopaque dye injected through a thin tube (catheter), which is threaded to the artery being studied, to detect and outline or highlight a blockage or defect in an artery |
Audiometry | Ears | Assessment of the ability to hear and distinguish sounds at specific pitches and volumes using headphones |
Auscultation | Heart | Listening with a stethoscope for abnormal heart sounds |
Barium x-ray studies | Esophagus, stomach, intestine, or rectum | X-ray study to detect ulcers, tumors, or other abnormalities |
Biopsy | Any tissue in the body | Removal and examination of a tissue sample under a microscope to check for cancer or another abnormality |
Blood pressure measurement | Usually an arm | Test for high or low blood pressure, usually using an inflatable cuff wrapped around the arm |
Spirometry | Lungs | Test of lung function that involves blowing into a measuring device |
Stress testing | Heart | Test of heart function during exertion using a treadmill or other exercise machine and electrocardiography (if people cannot exercise, a drug is used to simulate exercise’s effects) |
Thoracentesis | The space between the pleura, a two-layered membrane that covers the lungs and lines the chest wall (pleural space) | Removal of fluid from this space with a needle to detect abnormalities |
Thoracoscopy | Lungs | Examination of the lung surfaces, pleura, and pleural space through a viewing tube |
Tympanometry | Ears | Measurement of the resistance to pressure (impedance) in the middle ear using a device inserted in the ear and sound waves to help determine the cause of hearing loss |
Ultrasonography (ultrasound scanning) | Any part of the body | Imaging using sound waves to detect structural or functional abnormalities |
Urinalysis | Kidneys and urinary tract | Chemical analysis of a urine sample to detect protein, sugar, ketones, and blood cells |
Venography | Veins | X-ray study using a radiopaque dye (similar to arteriography) to detect blockage of a vein |
Blood tests | Usually a blood sample from an arm | Measurement of substances in the blood to evaluate organ function and to help diagnose and monitor various disorders |
Bone marrow aspiration | Hipbone or breastbone | Removal of a bone marrow sample by a needle for examination under a microscope to check for abnormalities in blood cells |
Bronchoscopy | Airways of the lungs | Direct examination with a viewing tube to check for a tumor or other abnormality |
Cardiac catheterization | Heart | Study of heart function and structure using a catheter inserted into a blood vessel and threaded to the heart |
Chorionic villus sampling | Placenta | Removal of a sample for examination under a microscope to check for abnormalities in the fetus |
Chromosomal analysis | Blood | Examination under a microscope to detect a genetic disorder or to determine a fetus’s sex |
Colonoscopy | Large intestine | Direct examination with a viewing tube to check for a tumor or other abnormality |
Colposcopy | Cervix | Direct examination of the cervix with a magnifying lens |
Computed tomography (CT) | Any part of the body | Computer-enhanced x-ray study to detect structural abnormalities |
Cone biopsy | Cervix | Removal and examination of a cone-shaped piece of tissue, usually using a heated wire loop or a laser |
Culture | A sample from any area of the body (usually a fluid such as blood or urine) | Growth and examination of microorganisms from the sample to identify infection with bacteria or fungi |
Dilation and curettage (D and C) | Cervix and uterus | Examination of a sample under a microscope to check for abnormalities in the uterine lining using a small, sharp instrument (curet). |
Dual x-ray absorptiometry (DEXA) | Skeleton, focusing on specific regions, usually the hip, spine, and wrist | Low-dose x-ray study to determine the thickness of bones |
Echocardiography | Heart | Study of heart structure and function using sound waves |
Electrocardiography (ECG) | Heart | Study of the heart’s electrical activity using electrodes attached to the arms, legs, and chest |
Electroencephalography (EEG) | Brain | Study of the brain’s electrical function using electrodes attached to the scalp |
Electromyography | Muscles | Recording of a muscle’s electrical activity using small needles inserted into the muscle |
Electrophysiologic testing | Heart | Test to evaluate rhythm or electrical conduction abnormalities using a catheter inserted into a blood vessel and threaded to the heart |
Endoscopic retrograde cholangiopancreatography (ERCP) | Biliary tract | X-ray study of the biliary tract done after injection of a radiopaque dye and using a flexible viewing tube |
Endoscopy | Digestive tract | Direct examination of internal structures using a flexible viewing tube |
Enzyme-linked immunosorbent assay (ELISA) | Usually blood | Test that involves mixing the sample of blood with substances that can trigger allergies (allergens) or with microorganisms to test for the presence of specific antibodies |
Fluoroscopy | Digestive tract, heart, or lungs | A continuous x-ray study that enables a doctor to see the inside of an organ as it functions |
Hysteroscopy | Uterus | Direct examination of the inside of the uterus with a flexible viewing tube |
Intravenous urography | Kidneys and urinary tract | X-ray study of the kidneys and urinary tract after a radiopaque dye is injected into a vein (intravenously) |
Joint aspiration | Joints, especially those of the shoulders, elbows, fingers, hips, knees, ankles, and toes | Removal and examination of fluid from the space within joints to check for blood cells, crystals formed from minerals, and microorganisms |
Laparoscopy | Abdomen | Direct examination using a viewing tube inserted through an incision in the abdomen to diagnose and treat abnormalities in the abdomen |
Magnetic resonance imaging (MRI) | Any part of the body | Imaging test using a strong magnetic field and radio waves to check for structural abnormalities |
Mammography | Breasts | X-ray study to check for breast cancer |
Mediastinoscopy | Chest | Direct examination of the area of the chest between the lungs using a viewing tube inserted through a small incision just above the breastbone |
Myelography | Spinal column | Simple or computer-enhanced x-ray study of the spinal column after injection of a radiopaque dye |
Nerve conduction study | Nerves | Test to determine how fast a nerve impulse travels using electrodes or needles inserted along the path of the nerve |
Occult blood test | Large intestine | Test to detect blood in stool |
Ophthalmoscopy | Eyes | Direct examination using a handheld device that shines light into the eye to detect abnormalities inside the eye |
Papanicolaou (Pap) test | Cervix | Examination of cells scraped from the cervix under a microscope to detect cancer |
Paracentesis | Abdomen | Insertion of a needle into the abdominal cavity to remove fluid for examination |
Percutaneous transhepatic cholangiography | Liver and biliary tract | X-ray study of the liver and biliary tract after a radiopaque dye is injected into the liver |
Positron emission tomography (PET) | Brain and heart | Imaging test using particles that release radiation (positrons) to detect abnormalities in function |
Pulmonary function tests | Lungs | Tests to measure the lungs’ capacity to hold air, to move air in and out of the body, and to exchange oxygen and carbon dioxide as people blow into a measuring device |
Radionuclide imaging | Many organs | Imaging test using particles that release radiation (radionuclides) to detect abnormalities in blood flow, structure, or function |
Reflex tests | Tendons | Tests using a physical stimulus (such as a light tap) to detect abnormalities in nerve function |
Retrograde urography | Bladder and ureters | X-ray study of the bladder and ureters after a radiopaque dye is inserted into the ureter |
Sigmoidoscopy | Rectum and last portion of the large intestine | Direct examination using a viewing tube to detect tumors or other abnormalities |
Skin allergy tests | Usually an arm or the back | Tests for allergies done by placing a solution containing a possible allergen on the skin, then pricking the skin with a needle |
Spinal tap (lumbar puncture) | Spinal canal | Removal of spinal fluid, using a needle inserted into the hipbone, to check for abnormalities in spinal fluid |
X-ray | Any part of the body | Imaging test using electromagnetic waves to create pictures of the inside of the body |
X-ray angiography | Blood vessels | X-ray study using radiopaque dye injected into blood vessels to detect blockages or abnormalities |
X-ray computed tomography (CT) | Any part of the body | Imaging test using x-rays and computer technology to create detailed cross-sectional images |
X-ray dual energy x-ray absorptiometry (DEXA) | Bones | Low-dose x-ray study to determine bone mineral density and diagnose osteoporosis |
X-ray fluoroscopy | Digestive tract, heart, or lungs | Continuous x-ray study that enables visualization of the inside of organs as they function |
X-ray mammography | Breasts | X-ray study used to screen for breast cancer or detect abnormalities |
X-ray projection radiography | Any part of the body | Basic x-ray imaging technique that produces 2D images |
X-ray radiography | Any part of the body | Imaging technique that uses x-rays to create pictures of the inside of the body |
X-ray voiding cystourethrography (VCUG) | Bladder and urethra | X-ray study using radiopaque dye to visualize the bladder and urethra during urination |
X-ray xeroradiography | Any part of the body | X-ray imaging technique using dry development process to produce images |
X-ray arthrography | Joints | X-ray study using contrast dye injected into a joint to visualize structures |
X-ray hysterosalpingography | Uterus and fallopian tubes | X-ray study using contrast dye to visualize the uterus and fallopian tubes |
X-ray intravenous pyelogram (IVP) | Kidneys and urinary tract | X-ray study using contrast dye to visualize the urinary system |
X-ray myelography | Spinal column | X-ray study using contrast dye injected into the spinal canal to visualize the spinal cord and nerve roots |
X-ray sialography | Salivary glands | X-ray study using contrast dye to visualize the salivary glands |
X-ray small bowel series | Small intestine | X-ray study using contrast dye to visualize the small intestine |
X-ray upper gastrointestinal (GI) series | Esophagus, stomach, and small intestine | X-ray study using contrast dye to visualize the upper GI tract |
X-ray voiding urethrography | Urethra | X-ray study using contrast dye to visualize the urethra during urination |
X-ray barium enema | Large intestine | X-ray study using contrast dye to visualize the colon and rectum |
X-ray barium swallow | Esophagus | X-ray study using contrast dye to visualize the esophagus and swallowing function |
X-ray barium follow-through | Small intestine | X-ray study using contrast dye to track the movement of barium through the small intestine |
X-ray barium meal | Stomach | X-ray study using contrast dye to visualize the stomach |
X-ray myelography | Spinal column | X-ray study using contrast dye injected into the spinal canal to visualize the spinal cord and nerve roots |
X-ray upper gastrointestinal (GI) series | Esophagus, stomach, and small intestine | X-ray study using contrast dye to visualize the upper GI tract |
Angioplasty | Blood vessels | Procedure to open narrowed or blocked blood vessels using a balloon-tipped catheter |
Aortography | Aorta | X-ray study using contrast dye to visualize the aorta |
Bronchography | Bronchi | X-ray study using contrast dye to visualize the bronchi |
Cerebral angiography | Blood vessels in the brain | X-ray study using contrast dye to visualize blood vessels in the brain |
Cholangiography | Biliary tract | X-ray study using contrast dye to visualize the biliary tract |
Coronary angiography | Coronary arteries | X-ray study using contrast dye to visualize the coronary arteries |
Cystography | Bladder | X-ray study using contrast dye to visualize the bladder |
Enteroclysis | Small intestine | X-ray study using contrast dye to visualize the small intestine |
Fistulography | Fistula | X-ray study using contrast dye to visualize a fistula |
Gallbladder radionuclide scan | Gallbladder | Imaging test using radionuclides to visualize the gallbladder |
Gastrointestinal motility studies | Gastrointestinal tract | Studies to assess the movement and function of the GI tract |
Heart catheterization | Heart | Study of heart function and blood flow using a catheter inserted into a blood vessel |
Hysterosalpingography | Uterus and fallopian tubes | X-ray study using contrast dye to visualize the uterus and fallopian tubes |
Intravenous pyelogram (IVP) | Kidneys and urinary tract | X-ray study using contrast dye to visualize the urinary system |
Lymphangiography | Lymphatic vessels | X-ray study using contrast dye to visualize the lymphatic vessels |
Magnetic resonance angiography (MRA) | Blood vessels | Imaging test using magnetic resonance imaging to visualize blood vessels |
Magnetic resonance cholangiopancreatography (MRCP) | Biliary and pancreatic ducts | Imaging test using magnetic resonance imaging to visualize the biliary and pancreatic ducts |
Myelography | Spinal column | X-ray study using contrast dye injected into the spinal canal to visualize the spinal cord and nerve roots |
Phlebography | Veins | X-ray study using contrast dye to visualize the veins |
Pulmonary angiography | Pulmonary arteries | X-ray study using contrast dye to visualize the pulmonary arteries |
Radionuclide angiography | Heart and blood vessels | Imaging test using radionuclides to visualize heart and blood vessel function |
Renal angiography | Kidneys and blood vessels | X-ray study using contrast dye to visualize the kidneys and blood vessels |
Sialography | Salivary glands | X-ray study using contrast dye to visualize the salivary glands |
Small bowel enteroclysis | Small intestine | X-ray study using contrast dye to visualize the small intestine |
Ventriculography | Heart ventricles | X-ray study using contrast dye to visualize the heart ventricles |
Vessel Doppler ultrasound | Blood vessels | Ultrasound test to visualize blood flow in the blood vessels |
Visual acuity test | Eyes | Test to measure the clarity of vision using an eye chart |
Visual field test | Eyes | Test to measure the extent of peripheral vision |
Vitamin B12 assay | Blood | Blood test to measure vitamin B12 levels |
Vitamin K assay | Blood | Blood test to measure vitamin K levels |
Von Willebrand factor antigen | Blood | Blood test to measure von Willebrand factor levels |
Von Willebrand factor multimers | Blood | Blood test to evaluate the size distribution of von Willebrand factor multimers |
Von Willebrand factor ristocetin cofactor activity | Blood | Blood test to measure the ristocetin cofactor activity of von Willebrand factor |
Von Willebrand factor collagen binding assay | Blood | Blood test to measure the collagen binding activity of von Willebrand factor |
Von Willebrand factor activity | Blood | Blood test to measure the activity of von Willebrand factor |
White blood cell count (WBC count) | Blood | Blood test to count the number of white blood cells |
White blood cell differential | Blood | Blood test to identify and count the different types of white blood cells |
X-ray | Any part of the body | Imaging test using electromagnetic radiation to visualize structures inside the body |
X-ray computed tomography (CT scan) | Any part of the body | Imaging test using x-rays and computer technology to create detailed cross-sectional images of the body |
X-ray, chest | Chest | X-ray study of the chest to check for abnormalities in the lungs and other structures |
X-ray, skeletal survey | Skeleton | X-ray study of the entire skeleton to detect abnormalities |
Arterial blood gases | Blood from an artery | Measurement of the levels of oxygen, carbon dioxide, and other gases in the blood |
Urine culture and sensitivity | Urine | Growth of microorganisms from a urine sample to identify the specific bacteria causing an infection and to determine the most effective antibiotic treatment |
Urine protein test | Urine | Measurement of the amount of protein in the urine to detect kidney damage or other medical conditions |
Urodynamic testing | Bladder and urethra | Assessment of the bladder's ability to hold and release urine and the pressure within the bladder and urethra during urination |
Vaginal wet mount | Vaginal discharge | Microscopic examination of vaginal discharge to diagnose infections and other vaginal conditions |
Vitamin B12 level | Blood | Measurement of vitamin B12 levels in the blood to assess vitamin deficiency or other medical conditions |
Vitamin D level | Blood | Measurement of vitamin D levels in the blood to assess bone health and overall well-being |
Voiding cystourethrogram (VCUG) | Bladder and urethra | X-ray study of the bladder and urethra during urination to detect abnormalities |
Von Willebrand factor (vWF) testing | Blood | Measurement of vWF levels and activity to diagnose bleeding disorders |
West Nile virus testing | Blood or cerebrospinal fluid | Detection of West Nile virus in blood or cerebrospinal fluid to diagnose infection |
Know the Blood Tests Reference Range
Imaging
Images obtained from imaging tests can be of the entire body or a specific portion of it. Imaging aids in the diagnosis, assessment of the severity of, and follow-up care of patients with disorders. The majority of imaging procedures are painless, relatively risk-free, and noninvasive (i.e., they don't call for cutting the skin or inserting a tool into the body).
The following may be used during imaging tests:
Radiation from procedures like computed tomography (CT), positron emission tomography (PET), x-rays, angiography, and radionuclide scanning
such as in ultrasonography, sound waves
as in magnetic resonance imaging (MRI), magnetic fields
Contrast agents are substances that are ingested, injected, or implanted to highlight or outline the tissue or organ being studied.
Glimpse into the Body: Endoscopic Exploration
In the realm of medical examination, a remarkable technique known as endoscopy takes center stage. This method employs a specialized viewing tube, commonly referred to as an endoscope, to offer direct visual access to the internal organs and cavities of the body. Flexibility characterizes most endoscopes, although rigid variants prove advantageous in certain scenarios. Fitted with a light source and a camera at its tip, the endoscope enables examiners to view captured images on a television monitor, eliminating the need to peer directly through the device. Notably, the endoscope often features a channel through which various tools can be introduced. Among these tools, one standout is designed for the precise removal of tissue samples.
The practice of endoscopy typically involves the passage of the viewing tube through pre-existing body openings, which may include:
Nasal Passages: Facilitating examinations of the voice box (laryngoscopy) or the lungs (bronchoscopy).
Oral Cavity: Enabling inspection of the esophagus (esophagoscopy), stomach (gastroscopy), and small intestine (upper gastrointestinal endoscopy).
Anus: For thorough evaluations of the large intestine, rectum, and anus (coloscopy).
Urethra: Enabling investigation of the bladder (cystoscopy).
Vaginal Canal: Providing a means to examine the uterus (hysteroscopy).
However, situations might arise where the creation of a new opening becomes necessary. In these instances, a small incision is made through the skin and underlying tissue layers, allowing the endoscope access to body cavities. This approach is utilized for observing the interiors of the following areas:
Joints (arthroscopy)
Abdominal Cavity (laparoscopy)
Mediastinal Region (mediastinoscopy), located in the chest between the lungs
Lungs and Pleura (thoracoscopy)
Quantifying Bodily Functions: The Art of Measurement
An essential facet of medical assessment involves the measurement and analysis of various bodily functions. This process often entails recording and scrutinizing the activities of different organs. For instance, the heart's electrical activity is quantified through electrocardiography (ECG), while the brain's electrical patterns are evaluated using electroencephalography (EEG). Pulmonary function tests gauge the lungs' capacity to hold and move air, as well as their efficiency in exchanging oxygen and carbon dioxide.
Unveiling Cellular Insights: The Biopsy Technique
When a deeper understanding of tissue is required, the biopsy procedure comes into play. This method entails the extraction of tissue samples from the body for meticulous examination. Under the microscope's discerning eye, cells are scrutinized, often with a focus on identifying abnormal cell patterns indicative of inflammation or underlying disorders like cancer. Commonly analyzed tissues encompass the skin, breast, lung, liver, kidney, and bone.
Decoding the Genetic Blueprint: Genetic Analysis Unveiled
In the vast realm of genetics, diagnostic techniques delve into chromosomes, genes, and DNA. These genetic diagnostic technologies frequently involve analyzing cells sourced from the skin, blood, or bone marrow. Applications of genetic testing span a broad spectrum:
Fetuses: Discerning the presence of genetic disorders
Children and Young Adults: Identifying existing disorders or assessing the risk of future ones
Adults: Aiding in the prediction of potential disorders in their descendants
The evolution of genetic diagnostic technology is swift, with methods ranging from gene segment replication to the detection of genetic alterations.
Navigating Risks and Rewards
Every medical test entails inherent risks, whether they involve the possibility of physical harm during the procedure or the potential necessity for subsequent testing if results appear abnormal. Often, these follow-up tests prove to be costlier and more perilous. The medical community weighs these risks against the information's utility.
In the realm of test interpretation, normal values are expressed as a range, reflective of average measurements within a healthy population. Notably, this range might differ slightly between genders and across age groups. Furthermore, variations may occur across different laboratories. As a result, when doctors interpret laboratory results, they also consider the specific laboratory's established normal range. While typical normal results can be found in tables, such as those listing blood test values, the individual's doctor remains the ultimate authority on the significance of test outcomes, accounting for laboratory-specific variations.
Disclaimer: This information is for educational purposes only. The intention is to provide assistance to patients and caregivers. The information provided here is referenced from MSD Manuals. However, it is important to consult your doctor for accurate medical advice and diagnosis.