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Which Diagnostic Test For What?

Which Diagnostic Test For What?

There are many different medical tests readily available. For a specific condition or a collection of connected disorders, numerous tests are employed. There are other illnesses for which other tests are frequently employed.
There are many reasons why tests are conducted, including
Screening
How to identify a condition
determining the seriousness of a problem so that a strategy for treatment can be made
Evaluating how well a treatment is working
A test may occasionally have multiple purposes. The presence of anemia, or too few red blood cells, can be detected with a blood test. After treatment, the same test may be conducted once more to see whether the quantity of red blood cells has stabilized. A problem can occasionally be treated concurrently with a screening or diagnostic test.
Most tests fall under one of the six categories listed below.
Examining bodily fluids
The fluids that are typically examined are
Blood
Urine
Cerebrospinal fluid is the fluid that surrounds the brain and spinal cord.
Joint fluid, also known as synovial fluid
Sweat, saliva, and digestive system fluid (such stomach secretions) are examined less frequently. When fluid builds up in the abdomen, generating ascites, or in the space between the two-layered membrane covering the lungs and lining the chest wall (pleura), causing pleural effusion, the fluids that are being tested are occasionally only present if a disease is present.

Test Procedure Sample Tested Procedure Description
AmniocentesisFluid from the sac surrounding the fetusAnalysis of fluid, removed by a needle inserted through the abdominal wall, to detect an abnormality in the fetus
Arteriography (angiography)Any artery in the body, commonly in the brain, heart, kidneys, aorta, or legsX-ray study using radiopaque dye injected through a thin tube (catheter), which is threaded to the artery being studied, to detect and outline or highlight a blockage or defect in an artery
AudiometryEarsAssessment of the ability to hear and distinguish sounds at specific pitches and volumes using headphones
AuscultationHeartListening with a stethoscope for abnormal heart sounds
Barium x-ray studiesEsophagus, stomach, intestine, or rectumX-ray study to detect ulcers, tumors, or other abnormalities
BiopsyAny tissue in the bodyRemoval and examination of a tissue sample under a microscope to check for cancer or another abnormality
Blood pressure measurementUsually an armTest for high or low blood pressure, usually using an inflatable cuff wrapped around the arm
SpirometryLungsTest of lung function that involves blowing into a measuring device
Stress testingHeartTest of heart function during exertion using a treadmill or other exercise machine and electrocardiography (if people cannot exercise, a drug is used to simulate exercise’s effects)
ThoracentesisThe space between the pleura, a two-layered membrane that covers the lungs and lines the chest wall (pleural space)Removal of fluid from this space with a needle to detect abnormalities
ThoracoscopyLungsExamination of the lung surfaces, pleura, and pleural space through a viewing tube
TympanometryEarsMeasurement of the resistance to pressure (impedance) in the middle ear using a device inserted in the ear and sound waves to help determine the cause of hearing loss
Ultrasonography (ultrasound scanning)Any part of the bodyImaging using sound waves to detect structural or functional abnormalities
UrinalysisKidneys and urinary tractChemical analysis of a urine sample to detect protein, sugar, ketones, and blood cells
VenographyVeinsX-ray study using a radiopaque dye (similar to arteriography) to detect blockage of a vein
Blood testsUsually a blood sample from an armMeasurement of substances in the blood to evaluate organ function and to help diagnose and monitor various disorders
Bone marrow aspirationHipbone or breastboneRemoval of a bone marrow sample by a needle for examination under a microscope to check for abnormalities in blood cells
BronchoscopyAirways of the lungsDirect examination with a viewing tube to check for a tumor or other abnormality
Cardiac catheterizationHeartStudy of heart function and structure using a catheter inserted into a blood vessel and threaded to the heart
Chorionic villus samplingPlacentaRemoval of a sample for examination under a microscope to check for abnormalities in the fetus
Chromosomal analysisBloodExamination under a microscope to detect a genetic disorder or to determine a fetus’s sex
ColonoscopyLarge intestineDirect examination with a viewing tube to check for a tumor or other abnormality
ColposcopyCervixDirect examination of the cervix with a magnifying lens
Computed tomography (CT)Any part of the bodyComputer-enhanced x-ray study to detect structural abnormalities
Cone biopsyCervixRemoval and examination of a cone-shaped piece of tissue, usually using a heated wire loop or a laser
CultureA sample from any area of the body (usually a fluid such as blood or urine)Growth and examination of microorganisms from the sample to identify infection with bacteria or fungi
Dilation and curettage (D and C)Cervix and uterusExamination of a sample under a microscope to check for abnormalities in the uterine lining using a small, sharp instrument (curet).
Dual x-ray absorptiometry (DEXA)Skeleton, focusing on specific regions, usually the hip, spine, and wristLow-dose x-ray study to determine the thickness of bones
EchocardiographyHeartStudy of heart structure and function using sound waves
Electrocardiography (ECG)HeartStudy of the heart’s electrical activity using electrodes attached to the arms, legs, and chest
Electroencephalography (EEG)BrainStudy of the brain’s electrical function using electrodes attached to the scalp
ElectromyographyMusclesRecording of a muscle’s electrical activity using small needles inserted into the muscle
Electrophysiologic testingHeartTest to evaluate rhythm or electrical conduction abnormalities using a catheter inserted into a blood vessel and threaded to the heart
Endoscopic retrograde cholangiopancreatography (ERCP)Biliary tractX-ray study of the biliary tract done after injection of a radiopaque dye and using a flexible viewing tube
EndoscopyDigestive tractDirect examination of internal structures using a flexible viewing tube
Enzyme-linked immunosorbent assay (ELISA)Usually bloodTest that involves mixing the sample of blood with substances that can trigger allergies (allergens) or with microorganisms to test for the presence of specific antibodies
FluoroscopyDigestive tract, heart, or lungsA continuous x-ray study that enables a doctor to see the inside of an organ as it functions
HysteroscopyUterusDirect examination of the inside of the uterus with a flexible viewing tube
Intravenous urographyKidneys and urinary tractX-ray study of the kidneys and urinary tract after a radiopaque dye is injected into a vein (intravenously)
Joint aspirationJoints, especially those of the shoulders, elbows, fingers, hips, knees, ankles, and toesRemoval and examination of fluid from the space within joints to check for blood cells, crystals formed from minerals, and microorganisms
LaparoscopyAbdomenDirect examination using a viewing tube inserted through an incision in the abdomen to diagnose and treat abnormalities in the abdomen
Magnetic resonance imaging (MRI)Any part of the bodyImaging test using a strong magnetic field and radio waves to check for structural abnormalities
MammographyBreastsX-ray study to check for breast cancer
MediastinoscopyChestDirect examination of the area of the chest between the lungs using a viewing tube inserted through a small incision just above the breastbone
MyelographySpinal columnSimple or computer-enhanced x-ray study of the spinal column after injection of a radiopaque dye
Nerve conduction studyNervesTest to determine how fast a nerve impulse travels using electrodes or needles inserted along the path of the nerve
Occult blood testLarge intestineTest to detect blood in stool
OphthalmoscopyEyesDirect examination using a handheld device that shines light into the eye to detect abnormalities inside the eye
Papanicolaou (Pap) testCervixExamination of cells scraped from the cervix under a microscope to detect cancer
ParacentesisAbdomenInsertion of a needle into the abdominal cavity to remove fluid for examination
Percutaneous transhepatic cholangiographyLiver and biliary tractX-ray study of the liver and biliary tract after a radiopaque dye is injected into the liver
Positron emission tomography (PET)Brain and heartImaging test using particles that release radiation (positrons) to detect abnormalities in function
Pulmonary function testsLungsTests to measure the lungs’ capacity to hold air, to move air in and out of the body, and to exchange oxygen and carbon dioxide as people blow into a measuring device
Radionuclide imagingMany organsImaging test using particles that release radiation (radionuclides) to detect abnormalities in blood flow, structure, or function
Reflex testsTendonsTests using a physical stimulus (such as a light tap) to detect abnormalities in nerve function
Retrograde urographyBladder and uretersX-ray study of the bladder and ureters after a radiopaque dye is inserted into the ureter
SigmoidoscopyRectum and last portion of the large intestineDirect examination using a viewing tube to detect tumors or other abnormalities
Skin allergy testsUsually an arm or the backTests for allergies done by placing a solution containing a possible allergen on the skin, then pricking the skin with a needle
Spinal tap (lumbar puncture)Spinal canalRemoval of spinal fluid, using a needle inserted into the hipbone, to check for abnormalities in spinal fluid
X-rayAny part of the bodyImaging test using electromagnetic waves to create pictures of the inside of the body
X-ray angiographyBlood vesselsX-ray study using radiopaque dye injected into blood vessels to detect blockages or abnormalities
X-ray computed tomography (CT)Any part of the bodyImaging test using x-rays and computer technology to create detailed cross-sectional images
X-ray dual energy x-ray absorptiometry (DEXA)BonesLow-dose x-ray study to determine bone mineral density and diagnose osteoporosis
X-ray fluoroscopyDigestive tract, heart, or lungsContinuous x-ray study that enables visualization of the inside of organs as they function
X-ray mammographyBreastsX-ray study used to screen for breast cancer or detect abnormalities
X-ray projection radiographyAny part of the bodyBasic x-ray imaging technique that produces 2D images
X-ray radiographyAny part of the bodyImaging technique that uses x-rays to create pictures of the inside of the body
X-ray voiding cystourethrography (VCUG)Bladder and urethraX-ray study using radiopaque dye to visualize the bladder and urethra during urination
X-ray xeroradiographyAny part of the bodyX-ray imaging technique using dry development process to produce images
X-ray arthrographyJointsX-ray study using contrast dye injected into a joint to visualize structures
X-ray hysterosalpingographyUterus and fallopian tubesX-ray study using contrast dye to visualize the uterus and fallopian tubes
X-ray intravenous pyelogram (IVP)Kidneys and urinary tractX-ray study using contrast dye to visualize the urinary system
X-ray myelographySpinal columnX-ray study using contrast dye injected into the spinal canal to visualize the spinal cord and nerve roots
X-ray sialographySalivary glandsX-ray study using contrast dye to visualize the salivary glands
X-ray small bowel seriesSmall intestineX-ray study using contrast dye to visualize the small intestine
X-ray upper gastrointestinal (GI) seriesEsophagus, stomach, and small intestineX-ray study using contrast dye to visualize the upper GI tract
X-ray voiding urethrographyUrethraX-ray study using contrast dye to visualize the urethra during urination
X-ray barium enemaLarge intestineX-ray study using contrast dye to visualize the colon and rectum
X-ray barium swallowEsophagusX-ray study using contrast dye to visualize the esophagus and swallowing function
X-ray barium follow-throughSmall intestineX-ray study using contrast dye to track the movement of barium through the small intestine
X-ray barium mealStomachX-ray study using contrast dye to visualize the stomach
X-ray myelographySpinal columnX-ray study using contrast dye injected into the spinal canal to visualize the spinal cord and nerve roots
X-ray upper gastrointestinal (GI) seriesEsophagus, stomach, and small intestineX-ray study using contrast dye to visualize the upper GI tract
AngioplastyBlood vesselsProcedure to open narrowed or blocked blood vessels using a balloon-tipped catheter
AortographyAortaX-ray study using contrast dye to visualize the aorta
BronchographyBronchiX-ray study using contrast dye to visualize the bronchi
Cerebral angiographyBlood vessels in the brainX-ray study using contrast dye to visualize blood vessels in the brain
CholangiographyBiliary tractX-ray study using contrast dye to visualize the biliary tract
Coronary angiographyCoronary arteriesX-ray study using contrast dye to visualize the coronary arteries
CystographyBladderX-ray study using contrast dye to visualize the bladder
EnteroclysisSmall intestineX-ray study using contrast dye to visualize the small intestine
FistulographyFistulaX-ray study using contrast dye to visualize a fistula
Gallbladder radionuclide scanGallbladderImaging test using radionuclides to visualize the gallbladder
Gastrointestinal motility studiesGastrointestinal tractStudies to assess the movement and function of the GI tract
Heart catheterizationHeartStudy of heart function and blood flow using a catheter inserted into a blood vessel
HysterosalpingographyUterus and fallopian tubesX-ray study using contrast dye to visualize the uterus and fallopian tubes
Intravenous pyelogram (IVP)Kidneys and urinary tractX-ray study using contrast dye to visualize the urinary system
LymphangiographyLymphatic vesselsX-ray study using contrast dye to visualize the lymphatic vessels
Magnetic resonance angiography (MRA)Blood vesselsImaging test using magnetic resonance imaging to visualize blood vessels
Magnetic resonance cholangiopancreatography (MRCP)Biliary and pancreatic ductsImaging test using magnetic resonance imaging to visualize the biliary and pancreatic ducts
MyelographySpinal columnX-ray study using contrast dye injected into the spinal canal to visualize the spinal cord and nerve roots
PhlebographyVeinsX-ray study using contrast dye to visualize the veins
Pulmonary angiographyPulmonary arteriesX-ray study using contrast dye to visualize the pulmonary arteries
Radionuclide angiographyHeart and blood vesselsImaging test using radionuclides to visualize heart and blood vessel function
Renal angiographyKidneys and blood vesselsX-ray study using contrast dye to visualize the kidneys and blood vessels
SialographySalivary glandsX-ray study using contrast dye to visualize the salivary glands
Small bowel enteroclysisSmall intestineX-ray study using contrast dye to visualize the small intestine
VentriculographyHeart ventriclesX-ray study using contrast dye to visualize the heart ventricles
Vessel Doppler ultrasoundBlood vesselsUltrasound test to visualize blood flow in the blood vessels
Visual acuity testEyesTest to measure the clarity of vision using an eye chart
Visual field testEyesTest to measure the extent of peripheral vision
Vitamin B12 assayBloodBlood test to measure vitamin B12 levels
Vitamin K assayBloodBlood test to measure vitamin K levels
Von Willebrand factor antigenBloodBlood test to measure von Willebrand factor levels
Von Willebrand factor multimersBloodBlood test to evaluate the size distribution of von Willebrand factor multimers
Von Willebrand factor ristocetin cofactor activityBloodBlood test to measure the ristocetin cofactor activity of von Willebrand factor
Von Willebrand factor collagen binding assayBloodBlood test to measure the collagen binding activity of von Willebrand factor
Von Willebrand factor activityBloodBlood test to measure the activity of von Willebrand factor
White blood cell count (WBC count)BloodBlood test to count the number of white blood cells
White blood cell differentialBloodBlood test to identify and count the different types of white blood cells
X-rayAny part of the bodyImaging test using electromagnetic radiation to visualize structures inside the body
X-ray computed tomography (CT scan)Any part of the bodyImaging test using x-rays and computer technology to create detailed cross-sectional images of the body
X-ray, chestChestX-ray study of the chest to check for abnormalities in the lungs and other structures
X-ray, skeletal surveySkeletonX-ray study of the entire skeleton to detect abnormalities
Arterial blood gasesBlood from an arteryMeasurement of the levels of oxygen, carbon dioxide, and other gases in the blood
Urine culture and sensitivityUrineGrowth of microorganisms from a urine sample to identify the specific bacteria causing an infection and to determine the most effective antibiotic treatment
Urine protein testUrineMeasurement of the amount of protein in the urine to detect kidney damage or other medical conditions
Urodynamic testingBladder and urethraAssessment of the bladder's ability to hold and release urine and the pressure within the bladder and urethra during urination
Vaginal wet mountVaginal dischargeMicroscopic examination of vaginal discharge to diagnose infections and other vaginal conditions
Vitamin B12 levelBloodMeasurement of vitamin B12 levels in the blood to assess vitamin deficiency or other medical conditions
Vitamin D levelBloodMeasurement of vitamin D levels in the blood to assess bone health and overall well-being
Voiding cystourethrogram (VCUG)Bladder and urethraX-ray study of the bladder and urethra during urination to detect abnormalities
Von Willebrand factor (vWF) testingBloodMeasurement of vWF levels and activity to diagnose bleeding disorders
West Nile virus testingBlood or cerebrospinal fluidDetection of West Nile virus in blood or cerebrospinal fluid to diagnose infection

Know the Blood Tests Reference Range

Imaging
Images obtained from imaging tests can be of the entire body or a specific portion of it. Imaging aids in the diagnosis, assessment of the severity of, and follow-up care of patients with disorders. The majority of imaging procedures are painless, relatively risk-free, and noninvasive (i.e., they don't call for cutting the skin or inserting a tool into the body).
The following may be used during imaging tests:
Radiation from procedures like computed tomography (CT), positron emission tomography (PET), x-rays, angiography, and radionuclide scanning such as in ultrasonography, sound waves as in magnetic resonance imaging (MRI), magnetic fields Contrast agents are substances that are ingested, injected, or implanted to highlight or outline the tissue or organ being studied.

Glimpse into the Body: Endoscopic Exploration
In the realm of medical examination, a remarkable technique known as endoscopy takes center stage. This method employs a specialized viewing tube, commonly referred to as an endoscope, to offer direct visual access to the internal organs and cavities of the body. Flexibility characterizes most endoscopes, although rigid variants prove advantageous in certain scenarios. Fitted with a light source and a camera at its tip, the endoscope enables examiners to view captured images on a television monitor, eliminating the need to peer directly through the device. Notably, the endoscope often features a channel through which various tools can be introduced. Among these tools, one standout is designed for the precise removal of tissue samples.
The practice of endoscopy typically involves the passage of the viewing tube through pre-existing body openings, which may include:
Nasal Passages: Facilitating examinations of the voice box (laryngoscopy) or the lungs (bronchoscopy).
Oral Cavity: Enabling inspection of the esophagus (esophagoscopy), stomach (gastroscopy), and small intestine (upper gastrointestinal endoscopy).
Anus: For thorough evaluations of the large intestine, rectum, and anus (coloscopy).
Urethra: Enabling investigation of the bladder (cystoscopy).
Vaginal Canal: Providing a means to examine the uterus (hysteroscopy).
However, situations might arise where the creation of a new opening becomes necessary. In these instances, a small incision is made through the skin and underlying tissue layers, allowing the endoscope access to body cavities. This approach is utilized for observing the interiors of the following areas:
Joints (arthroscopy)
Abdominal Cavity (laparoscopy)
Mediastinal Region (mediastinoscopy), located in the chest between the lungs
Lungs and Pleura (thoracoscopy)
Quantifying Bodily Functions: The Art of Measurement
An essential facet of medical assessment involves the measurement and analysis of various bodily functions. This process often entails recording and scrutinizing the activities of different organs. For instance, the heart's electrical activity is quantified through electrocardiography (ECG), while the brain's electrical patterns are evaluated using electroencephalography (EEG). Pulmonary function tests gauge the lungs' capacity to hold and move air, as well as their efficiency in exchanging oxygen and carbon dioxide.
Unveiling Cellular Insights: The Biopsy Technique
When a deeper understanding of tissue is required, the biopsy procedure comes into play. This method entails the extraction of tissue samples from the body for meticulous examination. Under the microscope's discerning eye, cells are scrutinized, often with a focus on identifying abnormal cell patterns indicative of inflammation or underlying disorders like cancer. Commonly analyzed tissues encompass the skin, breast, lung, liver, kidney, and bone.
Decoding the Genetic Blueprint: Genetic Analysis Unveiled
In the vast realm of genetics, diagnostic techniques delve into chromosomes, genes, and DNA. These genetic diagnostic technologies frequently involve analyzing cells sourced from the skin, blood, or bone marrow. Applications of genetic testing span a broad spectrum:
Fetuses: Discerning the presence of genetic disorders
Children and Young Adults: Identifying existing disorders or assessing the risk of future ones
Adults: Aiding in the prediction of potential disorders in their descendants
The evolution of genetic diagnostic technology is swift, with methods ranging from gene segment replication to the detection of genetic alterations.
Navigating Risks and Rewards
Every medical test entails inherent risks, whether they involve the possibility of physical harm during the procedure or the potential necessity for subsequent testing if results appear abnormal. Often, these follow-up tests prove to be costlier and more perilous. The medical community weighs these risks against the information's utility.
In the realm of test interpretation, normal values are expressed as a range, reflective of average measurements within a healthy population. Notably, this range might differ slightly between genders and across age groups. Furthermore, variations may occur across different laboratories. As a result, when doctors interpret laboratory results, they also consider the specific laboratory's established normal range. While typical normal results can be found in tables, such as those listing blood test values, the individual's doctor remains the ultimate authority on the significance of test outcomes, accounting for laboratory-specific variations.

Disclaimer: This information is for educational purposes only. The intention is to provide assistance to patients and caregivers. The information provided here is referenced from MSD Manuals. However, it is important to consult your doctor for accurate medical advice and diagnosis.