πŸ“’ Healthcare Trends & Expert Insights

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή A paper on microplastics accumulating in the brain was just published

πŸ’‘ Expert Opinion:

πŸ”— Source: https://www.nature.com/articles/s41591-024-03453-1

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή Questioning the dogma that high glycemic foods leads to hunger and increased intake. A randomized trial of different glycemic index consumption

πŸ’‘ Expert Opinion:

πŸ”— Source: https://t.co/gSok3Kmf6K

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή A.I. should be trained to reason like a team of multidisciplinary physicians, well suited for complex cases

πŸ’‘ Expert Opinion:

πŸ”— Source: https://www.nature.com/articles/d41586-025-00618-x

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή The promise of a personalized (neoantigen) vaccine for treating cancer, as seen by immune response bolstering against renal cell carcinoma in a Phase 1 trial

πŸ’‘ Expert Opinion:

πŸ”— Source: https://www.nature.com/articles/s41586-024-08507-5

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή Is generative AI capable of clinical reasoning?

πŸ’‘ Expert Opinion:

πŸ”— Source: https://t.co/Z6Y577tyb4

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή New example of opportunistic A.I. in medicine. Get a liver diagnosis from an echocardiogram

πŸ’‘ Expert Opinion:

πŸ”— Source: https://ai.nejm.org/doi/full/10.1056/AIoa2400948

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή How it may be possible to maintain integrity of the blood brain barrier that is dysregulated during aging

πŸ’‘ Expert Opinion:

πŸ”— Source: https://www.nature.com/articles/s41586-025-08589-9

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή Heart disease in women is frequently missed and discounted, even though it is the number one cause of death globally. A new study shows A.I. of the ECG can accurately identify heart disease risk in women

πŸ’‘ Expert Opinion:

πŸ”— Source: https://t.co/7rcHBeA7tl

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή This is how you can predict an individual's risk of an age-related disease 2 decades ahead of their showing up (along with other data). More on this

πŸ’‘ Expert Opinion:

πŸ”— Source: https://t.co/edAEOiF3QF

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή Peto's Paradoxβ€”that cancer does not increase with body size of mammalsβ€”was wrong. A new, comprehensive study of 263 species documents higher cancer prevalence with increasing body mass. Some large animals (e.g. elephants) have some built-in genetic adaptations

πŸ’‘ Expert Opinion:

πŸ”— Source: https://www.pnas.org/doi/10.1073/pnas.2422861122

πŸ•’ Posted on: March 5, 2025, 7:27 am

πŸ”Ή What is your pace of aging? A new Nature feature on molecular clocks by Heidi Ledford gets into the issues surrounding these tests (can is really can't)

πŸ’‘ Expert Opinion:

πŸ”— Source: https://www.nature.com/articles/d41586-025-00566-6

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή A 2-year open-label follow-up from the EMPA-KIDNEY trial found that empagliflozin continued to provide additional cardiorenal benefits for up to 12 months after discontinuation.

πŸ’‘ Expert Opinion: This reinforces the long-term protective effects of SGLT2 inhibitors in chronic kidney disease, suggesting sustained benefits even after stopping treatment.

πŸ”— Source: https://www.nejm.org/doi/full/10.1056/NEJMoa2409183

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή The development of MASLD follows a β€œ2-hit” theory, where lipid accumulation in hepatocytes is the first hit, and oxidative stress is the second.

πŸ’‘ Expert Opinion: This model highlights the multifactorial nature of MASLD progression, guiding targeted therapeutic strategies.

πŸ”— Source: https://t.co/htTmKSVL1h

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή Resistance training improves clinical and hepatic markers in MASLD patients.

πŸ’‘ Expert Opinion: Exercise remains a cornerstone of MASLD management, with resistance training providing significant metabolic and hepatic benefits.

πŸ”— Source: https://t.co/QsjAi4DhDN

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή GLP-1 RA use is not linked to an increased risk of suicidal ideation or self-injury.

πŸ’‘ Expert Opinion: This is reassuring for patients and clinicians concerned about the psychiatric safety profile of GLP-1 receptor agonists.

πŸ”— Source: https://link.springer.com/article/10.1007/s00125-024-06243-z

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή Comparison of leading new antiobesity drug candidates with semaglutide and tirzepatide.

πŸ’‘ Expert Opinion: With the rise of GLP-1-based therapies, this analysis provides valuable insights into the future of pharmacologic obesity management.

πŸ”— Source: https://t.co/c1zrjEGZEo

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή Combining pioglitazone with SGLT2 inhibitors may be more effective for reducing MASH risk than using either therapy alone.

πŸ’‘ Expert Opinion: This combination approach could offer a novel strategy for MASH management, targeting multiple metabolic pathways.

πŸ”— Source: https://t.co/zW8Q2CLO9m

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή Critical gaps remain in understanding long-term effects, mechanisms, and patient responses to GLP-1 receptor agonists.

πŸ’‘ Expert Opinion: Addressing these uncertainties is crucial for optimizing the use of GLP-1 therapies in obesity and diabetes.

πŸ”— Source: https://www.nature.com/articles/s41591-024-03380-1

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή Taking more steps daily is linked to a lower risk of all-cause mortality.

πŸ’‘ Expert Opinion: This supports step-based activity recommendations, reinforcing the importance of daily movement for longevity.

πŸ”— Source: https://t.co/h05Xff5Bnq

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή Metformin is being explored as a potential therapy for ischemic stroke.

πŸ’‘ Expert Opinion: Despite minor editorial issues, the paper provides a compelling review of metformin’s neuroprotective effects.

πŸ”— Source: https://dom-pubs.pericles-prod.literatumonline.com/doi/abs/10.1111/dom.16105

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή The first phase 3 trial of exenatide for neurodegeneration showed no statistically significant benefit in Parkinson’s disease.

πŸ’‘ Expert Opinion: This is a setback for neurodegenerative treatment research, but further studies may refine the approach.

πŸ”— Source: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02808-3/fulltext

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή The combination of sleep apnea and diabetes significantly raises the risk of cardiovascular disease, cancer, and dementia.

πŸ’‘ Expert Opinion: This underscores the importance of screening and treating both conditions to reduce long-term health risks.

πŸ”— Source: https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.16059

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή Light influences glucose and lipid homeostasis via the sympathetic nervous system.

πŸ’‘ Expert Opinion: This adds an intriguing dimension to metabolic regulation, suggesting potential chronotherapy interventions.

πŸ”— Source: https://www.science.org/doi/10.1126/sciadv.adp3284

πŸ•’ Posted on: March 5, 2025, 7:03 am

πŸ”Ή SGLT2 inhibitors outperform GLP-1 agonists and exercise in reducing epicardial adipose tissue.

πŸ’‘ Expert Opinion: This provides another cardiovascular benefit of SGLT2 inhibitors beyond glycemic control.

πŸ”— Source: https://dom-pubs.pericles-prod.literatumonline.com/doi/abs/10.1111/dom.16107

πŸ•’ Posted on: March 5, 2025, 5:30 am

πŸ”Ή Plasma Exchange (PLEX) success story shared at SCCM 2025.

πŸ’‘ Expert Opinion: Case presentation from @MDAndersonNews.

πŸ”— Source: https://t.co/LvmLbGkCcE

πŸ•’ Posted on: March 5, 2025, 5:29 am

πŸ”Ή Research on probiotic use in pediatrics.

πŸ’‘ Expert Opinion: Discusses controversies in clinical application.

πŸ”— Source: https://t.co/DJV8MOj01Q

πŸ•’ Posted on: March 5, 2025, 5:29 am

πŸ”Ή The Atmo wireless capsule shows correlation with SmartPill transit studies.

πŸ’‘ Expert Opinion: Potential new method for gastric motility assessments.

πŸ”— Source: https://t.co/y5nBDkARQV

πŸ•’ Posted on: March 5, 2025, 5:28 am

πŸ”Ή Case report on amoxicillin-clavulanate-induced liver and kidney failure.

πŸ’‘ Expert Opinion: Highlights the role of biopsy in diagnosis.

πŸ”— Source: https://t.co/K4YxftvTrJ

πŸ•’ Posted on: March 5, 2025, 5:28 am

πŸ”Ή Research on diacylglycerol O-acyltransferases in colon cancer.

πŸ’‘ Expert Opinion: Study by @TulaneMedicine and @AGA_Gastro.

πŸ”— Source: https://t.co/J146P2RfMV

πŸ•’ Posted on: March 5, 2025, 5:27 am

πŸ”Ή New study on stroke rehabilitation training using brain-computer interface.

πŸ’‘ Expert Opinion: Innovative motor imagery approach.

πŸ”— Source: https://t.co/Lt8V6vAmxe

πŸ•’ Posted on: March 5, 2025, 5:27 am

πŸ”Ή Top 5 wellness tips for cancer support by Jessica Whorton.

πŸ’‘ Expert Opinion: Practical guidance for patients and caregivers.

πŸ”— Source: https://t.co/tPq3RZQ4Lx

πŸ•’ Posted on: March 5, 2025, 5:26 am

πŸ”Ή Diagnosis of Tubercular Lymphadenitis.

πŸ’‘ Expert Opinion: Insights from Dr. P.V.N. Sarvani.

πŸ”— Source: https://t.co/fGtuSSDM7h

πŸ•’ Posted on: March 5, 2025, 5:26 am

πŸ”Ή Research on multimodal histopathologic models in breast cancer.

πŸ’‘ Expert Opinion: Work by @kevinmboehm and others.

πŸ”— Source: https://t.co/XgeoNEKZJA

πŸ•’ Posted on: March 5, 2025, 5:25 am

πŸ”Ή Texas physicians advocate at the TX Capitol.

πŸ’‘ Expert Opinion: Dr. John Flores meets lawmakers for physician rights.

πŸ”— Source: https://t.co/ZHcMUuLdJk

πŸ•’ Posted on: March 5, 2025, 5:25 am

πŸ”Ή Doctors demand PubMed access.

πŸ’‘ Expert Opinion: Calls for continued support for research accessibility.

πŸ”— Source: https://t.co/7NBc6T4v03

πŸ•’ Posted on: March 5, 2025, 5:24 am

πŸ”Ή Osler offers CPD resources for junior doctors.

πŸ’‘ Expert Opinion: A single platform for CPD support.

πŸ”— Source: https://t.co/BdhmZFPzF0

πŸ•’ Posted on: March 5, 2025, 5:23 am

πŸ”Ή Clinical case of a dye industry worker with poisoning symptoms.

πŸ’‘ Expert Opinion: Medical professionals discuss possible diagnoses.

πŸ”— Source: https://t.co/XfGjV7Iwge

πŸ•’ Posted on: March 5, 2025, 5:23 am

πŸ”Ή Childhood cancer remains underfunded and under-researched.

πŸ’‘ Expert Opinion: Statement from Wafaa M Rashed @UNGeneva.

πŸ”— Source: https://t.co/NBMNnqxmST

πŸ•’ Posted on: March 5, 2025, 5:23 am

πŸ”Ή IMA protests the appointment of a non-medical professional as RUHS VC.

πŸ’‘ Expert Opinion: Raises concerns about medical leadership qualifications.

πŸ”— Source: https://t.co/FkFeIP1tSJ

πŸ•’ Posted on: March 5, 2025, 5:22 am

πŸ”Ή A personal story about working in the social sector and navigating financial dependence.

πŸ’‘ Expert Opinion: Explores the intersection of feminism and identity in financial roles.

πŸ”— Source: https://t.co/COBOfCEgur

πŸ•’ Posted on: March 5, 2025, 5:21 am

πŸ”Ή A new article discusses plant-dominant low-protein diets as a strategy to mitigate chronic kidney disease progression.

πŸ’‘ Expert Opinion: Cites work of @sjoshimd and @kamkalantar.

πŸ”— Source: https://t.co/QWL2jUnKIl

πŸ•’ Posted on: February 28, 2025, 11:19 am

πŸ”Ή What is the most serious skin reaction related?

πŸ’‘ Expert Opinion: The closed Special Issue edited by Dr. Kazuhiro Mizukami welcomes your reading! Gastric Cancer: Diagnosis, Treatment, and Prevention. Papers published: 9.

πŸ”— Source: https://t.co/IQR5Ldbk9z

πŸ•’ Posted on: February 28, 2025, 11:05 am

πŸ”Ή BGICC25 Updates:

πŸ’‘ Expert Opinion: Prof. Jessica Leung on BI-RADS Updates and Breast Cancer Imaging.

πŸ”— Source: https://t.co/OTzvFTjbzp

πŸ•’ Posted on: February 28, 2025, 11:03 am

πŸ”Ή Evnia newsletter alert! February's newsletter is out

πŸ’‘ Expert Opinion: Seniors and students of MedTwitter what's your take on this statement? Context that CBME has allowed episiotomy to undergraduate students (after passing of 1st yr) under certifiable skills. Nowhere have they mentioned about incision to be given by UG during LSCS. Is this legal?

πŸ”— Source: https://t.co/CTqHJtIFt1