π Posted on: March 5, 2025, 7:27 am
πΉ A paper on microplastics accumulating in the brain was just published
π‘ Expert Opinion:
π Source: https://www.nature.com/articles/s41591-024-03453-1
π Posted on: March 5, 2025, 7:27 am
πΉ Questioning the dogma that high glycemic foods leads to hunger and increased intake. A randomized trial of different glycemic index consumption
π‘ Expert Opinion:
π Source: https://t.co/gSok3Kmf6K
π Posted on: March 5, 2025, 7:27 am
πΉ A.I. should be trained to reason like a team of multidisciplinary physicians, well suited for complex cases
π‘ Expert Opinion:
π Source: https://www.nature.com/articles/d41586-025-00618-x
π Posted on: March 5, 2025, 7:27 am
πΉ The promise of a personalized (neoantigen) vaccine for treating cancer, as seen by immune response bolstering against renal cell carcinoma in a Phase 1 trial
π‘ Expert Opinion:
π Source: https://www.nature.com/articles/s41586-024-08507-5
π Posted on: March 5, 2025, 7:27 am
πΉ Is generative AI capable of clinical reasoning?
π‘ Expert Opinion:
π Source: https://t.co/Z6Y577tyb4
π Posted on: March 5, 2025, 7:27 am
πΉ New example of opportunistic A.I. in medicine. Get a liver diagnosis from an echocardiogram
π‘ Expert Opinion:
π Source: https://ai.nejm.org/doi/full/10.1056/AIoa2400948
π Posted on: March 5, 2025, 7:27 am
πΉ How it may be possible to maintain integrity of the blood brain barrier that is dysregulated during aging
π‘ Expert Opinion:
π Source: https://www.nature.com/articles/s41586-025-08589-9
π Posted on: March 5, 2025, 7:27 am
πΉ Heart disease in women is frequently missed and discounted, even though it is the number one cause of death globally. A new study shows A.I. of the ECG can accurately identify heart disease risk in women
π‘ Expert Opinion:
π Source: https://t.co/7rcHBeA7tl
π Posted on: March 5, 2025, 7:27 am
πΉ This is how you can predict an individual's risk of an age-related disease 2 decades ahead of their showing up (along with other data). More on this
π‘ Expert Opinion:
π Source: https://t.co/edAEOiF3QF
π Posted on: March 5, 2025, 7:27 am
πΉ Peto's Paradoxβthat cancer does not increase with body size of mammalsβwas wrong. A new, comprehensive study of 263 species documents higher cancer prevalence with increasing body mass. Some large animals (e.g. elephants) have some built-in genetic adaptations
π‘ Expert Opinion:
π Source: https://www.pnas.org/doi/10.1073/pnas.2422861122
π Posted on: March 5, 2025, 7:27 am
πΉ What is your pace of aging? A new Nature feature on molecular clocks by Heidi Ledford gets into the issues surrounding these tests (can is really can't)
π‘ Expert Opinion:
π Source: https://www.nature.com/articles/d41586-025-00566-6
π Posted on: March 5, 2025, 7:03 am
πΉ A 2-year open-label follow-up from the EMPA-KIDNEY trial found that empagliflozin continued to provide additional cardiorenal benefits for up to 12 months after discontinuation.
π‘ Expert Opinion: This reinforces the long-term protective effects of SGLT2 inhibitors in chronic kidney disease, suggesting sustained benefits even after stopping treatment.
π Source: https://www.nejm.org/doi/full/10.1056/NEJMoa2409183
π Posted on: March 5, 2025, 7:03 am
πΉ The development of MASLD follows a β2-hitβ theory, where lipid accumulation in hepatocytes is the first hit, and oxidative stress is the second.
π‘ Expert Opinion: This model highlights the multifactorial nature of MASLD progression, guiding targeted therapeutic strategies.
π Source: https://t.co/htTmKSVL1h
π Posted on: March 5, 2025, 7:03 am
πΉ Resistance training improves clinical and hepatic markers in MASLD patients.
π‘ Expert Opinion: Exercise remains a cornerstone of MASLD management, with resistance training providing significant metabolic and hepatic benefits.
π Source: https://t.co/QsjAi4DhDN
π Posted on: March 5, 2025, 7:03 am
πΉ GLP-1 RA use is not linked to an increased risk of suicidal ideation or self-injury.
π‘ Expert Opinion: This is reassuring for patients and clinicians concerned about the psychiatric safety profile of GLP-1 receptor agonists.
π Source: https://link.springer.com/article/10.1007/s00125-024-06243-z
π Posted on: March 5, 2025, 7:03 am
πΉ Comparison of leading new antiobesity drug candidates with semaglutide and tirzepatide.
π‘ Expert Opinion: With the rise of GLP-1-based therapies, this analysis provides valuable insights into the future of pharmacologic obesity management.
π Source: https://t.co/c1zrjEGZEo
π Posted on: March 5, 2025, 7:03 am
πΉ Combining pioglitazone with SGLT2 inhibitors may be more effective for reducing MASH risk than using either therapy alone.
π‘ Expert Opinion: This combination approach could offer a novel strategy for MASH management, targeting multiple metabolic pathways.
π Source: https://t.co/zW8Q2CLO9m
π Posted on: March 5, 2025, 7:03 am
πΉ Critical gaps remain in understanding long-term effects, mechanisms, and patient responses to GLP-1 receptor agonists.
π‘ Expert Opinion: Addressing these uncertainties is crucial for optimizing the use of GLP-1 therapies in obesity and diabetes.
π Source: https://www.nature.com/articles/s41591-024-03380-1
π Posted on: March 5, 2025, 7:03 am
πΉ Taking more steps daily is linked to a lower risk of all-cause mortality.
π‘ Expert Opinion: This supports step-based activity recommendations, reinforcing the importance of daily movement for longevity.
π Source: https://t.co/h05Xff5Bnq
π Posted on: March 5, 2025, 7:03 am
πΉ Metformin is being explored as a potential therapy for ischemic stroke.
π‘ Expert Opinion: Despite minor editorial issues, the paper provides a compelling review of metforminβs neuroprotective effects.
π Source: https://dom-pubs.pericles-prod.literatumonline.com/doi/abs/10.1111/dom.16105
π Posted on: March 5, 2025, 7:03 am
πΉ The first phase 3 trial of exenatide for neurodegeneration showed no statistically significant benefit in Parkinsonβs disease.
π‘ Expert Opinion: This is a setback for neurodegenerative treatment research, but further studies may refine the approach.
π Source: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02808-3/fulltext
π Posted on: March 5, 2025, 7:03 am
πΉ The combination of sleep apnea and diabetes significantly raises the risk of cardiovascular disease, cancer, and dementia.
π‘ Expert Opinion: This underscores the importance of screening and treating both conditions to reduce long-term health risks.
π Source: https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.16059
π Posted on: March 5, 2025, 7:03 am
πΉ Light influences glucose and lipid homeostasis via the sympathetic nervous system.
π‘ Expert Opinion: This adds an intriguing dimension to metabolic regulation, suggesting potential chronotherapy interventions.
π Source: https://www.science.org/doi/10.1126/sciadv.adp3284
π Posted on: March 5, 2025, 7:03 am
πΉ SGLT2 inhibitors outperform GLP-1 agonists and exercise in reducing epicardial adipose tissue.
π‘ Expert Opinion: This provides another cardiovascular benefit of SGLT2 inhibitors beyond glycemic control.
π Source: https://dom-pubs.pericles-prod.literatumonline.com/doi/abs/10.1111/dom.16107
π Posted on: March 5, 2025, 5:30 am
πΉ Plasma Exchange (PLEX) success story shared at SCCM 2025.
π‘ Expert Opinion: Case presentation from @MDAndersonNews.
π Source: https://t.co/LvmLbGkCcE
π Posted on: March 5, 2025, 5:29 am
πΉ Research on probiotic use in pediatrics.
π‘ Expert Opinion: Discusses controversies in clinical application.
π Source: https://t.co/DJV8MOj01Q
π Posted on: March 5, 2025, 5:29 am
πΉ The Atmo wireless capsule shows correlation with SmartPill transit studies.
π‘ Expert Opinion: Potential new method for gastric motility assessments.
π Source: https://t.co/y5nBDkARQV
π Posted on: March 5, 2025, 5:28 am
πΉ Case report on amoxicillin-clavulanate-induced liver and kidney failure.
π‘ Expert Opinion: Highlights the role of biopsy in diagnosis.
π Source: https://t.co/K4YxftvTrJ
π Posted on: March 5, 2025, 5:28 am
πΉ Research on diacylglycerol O-acyltransferases in colon cancer.
π‘ Expert Opinion: Study by @TulaneMedicine and @AGA_Gastro.
π Source: https://t.co/J146P2RfMV
π Posted on: March 5, 2025, 5:27 am
πΉ New study on stroke rehabilitation training using brain-computer interface.
π‘ Expert Opinion: Innovative motor imagery approach.
π Source: https://t.co/Lt8V6vAmxe
π Posted on: March 5, 2025, 5:27 am
πΉ Top 5 wellness tips for cancer support by Jessica Whorton.
π‘ Expert Opinion: Practical guidance for patients and caregivers.
π Source: https://t.co/tPq3RZQ4Lx
π Posted on: March 5, 2025, 5:26 am
πΉ Diagnosis of Tubercular Lymphadenitis.
π‘ Expert Opinion: Insights from Dr. P.V.N. Sarvani.
π Source: https://t.co/fGtuSSDM7h
π Posted on: March 5, 2025, 5:26 am
πΉ Research on multimodal histopathologic models in breast cancer.
π‘ Expert Opinion: Work by @kevinmboehm and others.
π Source: https://t.co/XgeoNEKZJA
π Posted on: March 5, 2025, 5:25 am
πΉ Texas physicians advocate at the TX Capitol.
π‘ Expert Opinion: Dr. John Flores meets lawmakers for physician rights.
π Source: https://t.co/ZHcMUuLdJk
π Posted on: March 5, 2025, 5:25 am
πΉ Doctors demand PubMed access.
π‘ Expert Opinion: Calls for continued support for research accessibility.
π Source: https://t.co/7NBc6T4v03
π Posted on: March 5, 2025, 5:24 am
πΉ Osler offers CPD resources for junior doctors.
π‘ Expert Opinion: A single platform for CPD support.
π Source: https://t.co/BdhmZFPzF0
π Posted on: March 5, 2025, 5:23 am
πΉ Clinical case of a dye industry worker with poisoning symptoms.
π‘ Expert Opinion: Medical professionals discuss possible diagnoses.
π Source: https://t.co/XfGjV7Iwge
π Posted on: March 5, 2025, 5:23 am
πΉ Childhood cancer remains underfunded and under-researched.
π‘ Expert Opinion: Statement from Wafaa M Rashed @UNGeneva.
π Source: https://t.co/NBMNnqxmST
π Posted on: March 5, 2025, 5:23 am
πΉ IMA protests the appointment of a non-medical professional as RUHS VC.
π‘ Expert Opinion: Raises concerns about medical leadership qualifications.
π Source: https://t.co/FkFeIP1tSJ
π Posted on: March 5, 2025, 5:22 am
πΉ A personal story about working in the social sector and navigating financial dependence.
π‘ Expert Opinion: Explores the intersection of feminism and identity in financial roles.
π Source: https://t.co/COBOfCEgur
π Posted on: March 5, 2025, 5:21 am
πΉ A new article discusses plant-dominant low-protein diets as a strategy to mitigate chronic kidney disease progression.
π‘ Expert Opinion: Cites work of @sjoshimd and @kamkalantar.
π Source: https://t.co/QWL2jUnKIl
π Posted on: February 28, 2025, 11:19 am
πΉ What is the most serious skin reaction related?
π‘ Expert Opinion: The closed Special Issue edited by Dr. Kazuhiro Mizukami welcomes your reading! Gastric Cancer: Diagnosis, Treatment, and Prevention. Papers published: 9.
π Source: https://t.co/IQR5Ldbk9z
π Posted on: February 28, 2025, 11:05 am
πΉ BGICC25 Updates:
π‘ Expert Opinion: Prof. Jessica Leung on BI-RADS Updates and Breast Cancer Imaging.
π Source: https://t.co/OTzvFTjbzp
π Posted on: February 28, 2025, 11:03 am
πΉ Evnia newsletter alert! February's newsletter is out
π‘ Expert Opinion: Seniors and students of MedTwitter what's your take on this statement? Context that CBME has allowed episiotomy to undergraduate students (after passing of 1st yr) under certifiable skills. Nowhere have they mentioned about incision to be given by UG during LSCS. Is this legal?
π Source: https://t.co/CTqHJtIFt1