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Aortic Stenosis, Heart Failure, and Aortic Valve Replacement

This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.

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Coronary Revascularization Guided With Fractional Flow Reserve or Instantaneous Wave-Free Ratio

This study compares long-term outcomes of instantaneous wave-free ratio and fractional flow reserve-based strategies to guide revascularization.

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Age-Stratified Risk Categories for Cardiovascular Disease Prevention Therapies

This Viewpoint describes age-specific risk thresholds for cardiovascular disease prevention therapies.

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Dual-Antiplatelet Therapy After Drug-Eluting Stenting in ACS

This systematic review and network meta-analysis investigates the optimal duration of dual antiplatelet therapy in patients with acute coronary syndromes (ACS) undergoing percutaneous coronary interve

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Amiodarone or Implantable Cardioverter-Defibrillator in Chagas Cardiomyopathy

This randomized clinical trial assesses whether cardioverter-defibrillator implantation is more effective than amiodarone therapy for the primary prevention of all-cause mortality and secondary preven

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Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure

This study assesses the safety and efficacy of a novel, leadless, left ventricular endocardial pacing system for patients at high risk for a cardiac resynchronization therapy upgrade or whose coronary

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Prehospital Pulse-Dose Glucocorticoid in STEMI

This randomized clinical trial investigates if prehospital pulse-dose glucocorticoid treatment has a cardioprotective effect in patients with ST-segment elevation myocardial infarction (STEMI).

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Tombstone Pattern Electrocardiogram in a Young Woman

A woman in her mid-20s presented with acute fever, chest pain, and exertional dyspnea.

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Estimated Long-Term Benefits of Finerenone in Heart Failure

This prespecified analysis of the Finerenone Trial to Investigate the Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) randomized clinical trial investigates the lo

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Lipoprotein(a) and Long-Term Plaque Progression, Low-Density Plaque, and Pericoronary Inflammation

This study investigates the impact of lipoprotein(a) levels on long-term coronary artery plaque progression, high-risk plaque, and pericoronary adipose tissue inflammation.

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