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Life satisfaction among over-50s in England higher than before pandemic, study finds

Research shows happiness levels have bounced back post-Covid, although depression also remains more commonPeople 50 and over in England have greater life satisfaction and sense life is more worthwhile

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Olpasiran, Oxidized Phospholipids, and Systemic Inflammatory Biomarkers

The OCEAN(a)-DOSE multicenter randomized clinical trial among 281 patients with atherosclerotic cardiovascular disease assesses the effects of olpasiran on oxidized phospholipids, high-sensitivity int

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Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis

This Viewpoint advocates for prompt aortic valve replacement (rather than clinical surveillance) as the default strategy for patients with asymptomatic severe aortic stenosis.

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Arrhythmic Risk Stratification of Carriers of FLNCtv

This cohort study investigates the arrhythmic risk profile of carriers of filamin C truncating variants (FLNCtv) and the risk factors associated with the risk of life-threatening ventricular arrhythmi

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Intensive Blood Pressure Control in Older Adults

To the Editor We read with interest the article by Guo et al that used data from a community-based intervention led by nonphysician health care practitioners in rural China.

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FDA OKs Mirdametinib for Neurofibromatosis Type 1

(MedPage Today) -- The FDA on Tuesday approved mirdametinib (Gomekli) for adults and kids ages 2 and up with neurofibromatosis type 1 (NF1).

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Coming to You From the 'Department of Hallway Medicine'

(MedPage Today) -- The Pitt, a new medical drama drawing viewers into a fictional emergency department (ED), recently premiered on HBO.

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Alzheimer's Test Detects Tau Pathology Before Tangles Form

(MedPage Today) -- A cerebrospinal fluid (CSF) biomarker test detected tau protein in Alzheimer's disease years before it formed into pathologic fibrillary tangles.

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STAT+: RFK Jr. could resurrect a vaccine safety board — what it means

This week in health policy and politics: Reviving a defunct vaccine panel, NIH funding cuts on hold, DOGE's federal worker buyouts paused.

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Opinion: Health workers face a stark choice: become collaborators or resisters

“Authoritarian regimes often rely on doctors and other health workers to provide a facade of legitimacy and willing hands armed with scalpels, syringes, pens, or simply locks on doors,” writesR

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